BDBM50180431 CHEMBL381541::N-[1-(3-Bromo-phenylamino)-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-8-yl]-acrylamide

SMILES Brc1cccc(Nc2ncnc3Oc4ccc(NC(=O)C=C)cc4CNc23)c1

InChI Key InChIKey=GFAHXMGLSFRQDM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180431   

TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180431(N-[1-(3-Bromo-phenylamino)-10,11-dihydro-5-oxa-2,4...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of EGFR autophosphorylation in DiFi cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180431(N-[1-(3-Bromo-phenylamino)-10,11-dihydro-5-oxa-2,4...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed