BDBM50180443 (3-Chloro-4-fluoro-phenyl)-(8-methoxy-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-amine::CHEMBL426124

SMILES COc1ccc2Oc3ncnc(Nc4ccc(F)c(Cl)c4)c3NCc2c1

InChI Key InChIKey=WFZQPBLGVOTMEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180443   

TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180443((3-Chloro-4-fluoro-phenyl)-(8-methoxy-10,11-dihydr...)
Affinity DataIC50: 900nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180443((3-Chloro-4-fluoro-phenyl)-(8-methoxy-10,11-dihydr...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of EGFR autophosphorylation in DiFi cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed