BDBM50180553 2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(1-methyl-1H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane::CHEMBL206983

SMILES Cn1nnnc1C1CC2(NC1CCC2OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180553   

TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180553(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(1-methyl-...)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]-labeled substance P from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180553(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(1-methyl-...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [35S]-labeled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed