BDBM50180575 4-(1,3-bis(2-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxy-4-oxobut-2-enoic acid::CHEMBL202166

SMILES OC(=O)C(=O)\C=C(/O)c1cn(Cc2ccccc2F)c(=O)n(Cc2ccccc2F)c1=O

InChI Key InChIKey=YDLORTWEOBCEIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180575   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50180575(4-(1,3-bis(2-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetra...)
Affinity DataIC50: 600nMAssay Description:Inhibition of strand transfer step of wt HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50180575(4-(1,3-bis(2-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetra...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 3' processing step of wt HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed