BDBM50180602 3-Benzyl-4-oxo-4-((4-phenylethynyl)phenyl)butyric acid::CHEMBL201206

SMILES OC(=O)CC(Cc1ccccc1)C(=O)c1ccc(cc1)C#Cc1ccccc1

InChI Key InChIKey=QTFXITWPRZRHMV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50180602   

TargetMacrophage metalloelastase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50180602(3-Benzyl-4-oxo-4-((4-phenylethynyl)phenyl)butyric ...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50180602(3-Benzyl-4-oxo-4-((4-phenylethynyl)phenyl)butyric ...)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibitory activity against MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50180602(3-Benzyl-4-oxo-4-((4-phenylethynyl)phenyl)butyric ...)
Affinity DataIC50: 9.29E+3nMAssay Description:Inhibitory activity against MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed