BDBM50180663 CHEBI:7572::CHEMBL1275655

SMILES COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1

InChI Key InChIKey=SVJMLYUFVDMUHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50180663   

TargetPotassium channel subfamily K member 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180663BDBM50180663(CHEMBL1275655 | CHEBI:7572)
Affinity DataIC50: 430nMAssay Description:Inhibition of human TREK1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPotassium two pore domain channel subfamily K member 2(Bovine)
University of Clermont Auvergne

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180663BDBM50180663(CHEMBL1275655 | CHEBI:7572)
Affinity DataIC50: 750nMAssay Description:Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Federal University of Parana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180663BDBM50180663(CHEMBL1275655 | CHEBI:7572)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in human MCF7/MX cells mediated mitoxantrone efflux assessed as intracellular mitoxantrone level and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed