BDBM50180733 5-Methyl-2-pyridin-2-yl-1H-benzoimidazole::5-methyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole::5-methyl-2-pyridin-2-yl-1(3)H-benzoimidazole::CHEMBL352049::US8748618, LD-2-11

SMILES Cc1ccc2nc([nH]c2c1)-c1ccccn1

InChI Key InChIKey=HFYFOFMVURXVSD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50180733   

TargetCore-binding factor subunit beta(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50180733(5-Methyl-2-pyridin-2-yl-1H-benzoimidazole | 5-meth...)
Affinity DataIC50:  2.90E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetMethionine aminopeptidase 2(Human)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50180733(5-Methyl-2-pyridin-2-yl-1H-benzoimidazole | 5-meth...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Human)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50180733(5-Methyl-2-pyridin-2-yl-1H-benzoimidazole | 5-meth...)
Affinity DataIC50:  3.26E+4nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180733(5-Methyl-2-pyridin-2-yl-1H-benzoimidazole | 5-meth...)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of Co2+ loaded MetAP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed