BDBM50181307 4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)-1,5-naphthyridin-2(1H)-one::CHEMBL205405

SMILES CN1CCN(c2ccc3nc(-c4c(N)c5ncccc5[nH]c4=O)[nH]c3c2)CC1

InChI Key InChIKey=KCJHQDVGQZJZAJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181307   

LigandChemical structure of BindingDB Monomer ID 50181307BDBM50181307(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chiron

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50181307BDBM50181307(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181307BDBM50181307(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181307BDBM50181307(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50: 74nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed