BDBM50181867 4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropylamino)--[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-3-nitrobenzenesulfonamide::CHEMBL379895

SMILES CN(C)CC[C@@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(C)(C)CC1

InChI Key InChIKey=DWEHITNKTMMZBR-VWLOTQADSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50181867   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181867(4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi:  252nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181867(4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181867(4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi:  3.85E+3nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181867(4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataEC50:  9.50E+3nMAssay Description:Activity towards mouse FL5.12 cell line transfected with Bcl-XL in presence of gelatinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181867(4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataEC50:  1.61E+4nMAssay Description:Activity towards mouse FL5.12 cell line transfected with Bcl-XL in presence of 3% fetal bovine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed