BDBM50181868 CHEMBL434952::N-[4'-(3-hydroxypropyl)-2'-methoxybiphenyl-4-carbonyl]-3-nitro-4-(2-(phenylsulfanylethylamino)benzenesulfonamide

SMILES COc1cc(CCCO)ccc1-c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O

InChI Key InChIKey=GGWKUJZJEAKEPL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181868   

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181868(N-[4'-(3-hydroxypropyl)-2'-methoxybiphenyl-4-carbo...)
Affinity DataKi:  22nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181868(N-[4'-(3-hydroxypropyl)-2'-methoxybiphenyl-4-carbo...)
Affinity DataKi:  721nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181868(N-[4'-(3-hydroxypropyl)-2'-methoxybiphenyl-4-carbo...)
Affinity DataKi:  2.96E+3nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed