BDBM50181874 CHEMBL201670::N-[2'-methoxy-4'-(3-morpholin-4-yl-3-oxopropyl)biphenyl-4-carbonyl]-3-nitro-4-(2-phenylsulfanylethylamino)benzenesulfonamide

SMILES COc1cc(CCC(=O)N2CCOCC2)ccc1-c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O

InChI Key InChIKey=XXGDZWWCGYEYSL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181874   

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181874(N-[2'-methoxy-4'-(3-morpholin-4-yl-3-oxopropyl)bip...)
Affinity DataKi:  58nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181874(N-[2'-methoxy-4'-(3-morpholin-4-yl-3-oxopropyl)bip...)
Affinity DataKi:  366nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181874(N-[2'-methoxy-4'-(3-morpholin-4-yl-3-oxopropyl)bip...)
Affinity DataKi:  790nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed