BDBM50181892 4-{4-[3-nitro-4-(2-phenylsulfanylethylamino)benzenesulfonylaminocarbonyl]phenyl}piperazine-1-carboxylic acid tert-butyl ester::CHEMBL202540

SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O

InChI Key InChIKey=JOSXDEOFVWZBBY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181892   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181892(4-{4-[3-nitro-4-(2-phenylsulfanylethylamino)benzen...)
Affinity DataKi:  396nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181892(4-{4-[3-nitro-4-(2-phenylsulfanylethylamino)benzen...)
Affinity DataKi:  2.88E+3nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181892(4-{4-[3-nitro-4-(2-phenylsulfanylethylamino)benzen...)
Affinity DataKi:  3.35E+3nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed