BDBM50182436 CHEMBL3818801

SMILES O=C1\C(Cc2cc3OCOc3cc12)=C\C1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=VXQFGUJASGKRMS-VXLYETTFSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182436   

TargetAcetylcholinesterase(Human)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182436(CHEMBL3818801)
Affinity DataKi:  980nMAssay Description:Mixed inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Horse)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182436(CHEMBL3818801)
Affinity DataKi:  7.25E+3nMAssay Description:Non-competitive inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Horse)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182436(CHEMBL3818801)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Mouse)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182436(CHEMBL3818801)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of mouse BACE-1 preincubated for 10 mins followed by fluorescent peptide substrate addition measured for 30 mins by fluorescence plate rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Human)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182436(CHEMBL3818801)
Affinity DataIC50:  755nMAssay Description:Inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed