BDBM50182718 4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-5-methyl-1H-pyrazol-3-yl)-6-ethylbenzene-1,3-diol::CHEMBL204734

SMILES CCc1cc(-c2n[nH]c(C)c2-c2cccc3OCCOc23)c(O)cc1O

InChI Key InChIKey=VLQZFFMOEQUMBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182718   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182718(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-5-methy...)
Affinity DataIC50: 148nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182718(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-5-methy...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed