BDBM50183522 5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine::CHEMBL204753

SMILES Cc1sccc1NC(=O)Nc1nc2nn(C)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=OFJBHNZSLRFALF-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50183522   

TargetAdenosine receptor A3(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50183522(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50183522(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50183522(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50183522(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed