BDBM50183546 CHEMBL383071::S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylbutyl)-piperidine oxalate

SMILES C[C@@H](CCN1CCC(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccccc1

InChI Key InChIKey=YEGPPYAKYLLLMH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50183546   

TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50183546(S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]RTI-55 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50183546(S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [3H]DA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183546(S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(...)
Affinity DataKi:  30nMAssay Description:Displacement of [125I]RTI-55 from SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183546(S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(...)
Affinity DataKi:  40nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183546(S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(...)
Affinity DataKi:  75nMAssay Description:Inhibition of [3H]5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183546(S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed