BDBM50183785 (S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyphenyl)pentanoyl)-N-methylpiperidine-2-carboxamide::CHEMBL207756

SMILES CC[C@@H]([C@H](C(=O)N1CCCC[C@H]1C(=O)NC)c1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=ZQORGANDVNQVJF-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50183785   

TargetCollagenase 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183785((S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyph...)
Affinity DataKi:  7nMAssay Description:Binding affinity to recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183785((S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyph...)
Affinity DataKi:  8nMAssay Description:Binding affinity to recombinant TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183785((S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyph...)
Affinity DataKi:  11nMAssay Description:Binding affinity to recombinant MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183785((S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyph...)
Affinity DataKi:  25nMAssay Description:Binding affinity to recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183785((S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyph...)
Affinity DataIC50: 836nMAssay Description:Inhibition of LPS/interferon gamma-stimulated TNFalpha release from HPBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed