BDBM50183800 3-isopropyl-1-(4-(methylsulfonyl)phenyl)-1-(1-(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)phenyl)ethyl)urea::CHEMBL207559

SMILES CC(C)NC(=O)N(C(C)c1cccc(c1)-c1cc(cc2cccnc12)C(C)(C)S(C)(=O)=O)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=MIKQDQMGJFMIAZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50183800   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183800(3-isopropyl-1-(4-(methylsulfonyl)phenyl)-1-(1-(3-(...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183800(3-isopropyl-1-(4-(methylsulfonyl)phenyl)-1-(1-(3-(...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human GST-PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183800(3-isopropyl-1-(4-(methylsulfonyl)phenyl)-1-(1-(3-(...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human GST-PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183800(3-isopropyl-1-(4-(methylsulfonyl)phenyl)-1-(1-(3-(...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human GST-PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183800(3-isopropyl-1-(4-(methylsulfonyl)phenyl)-1-(1-(3-(...)
Affinity DataIC50: 400nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed