BDBM50184349 (Z)-4-[6-((Z)-3-carboxy-3-hydroxy-acryloyl)-1-(4-fluoro-benzyl)-4-oxo-1,4-dihydro-quinolin-3-yl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL377501
SMILES OC(=O)C(=O)CC(=O)c1ccc2n(Cc3ccc(F)cc3)cc(C(=O)CC(=O)C(O)=O)c(=O)c2c1
InChI Key InChIKey=MMZRUVLLFMTCOG-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50184349
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by gel-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity in presence of MgCl2More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MnCl2More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Facult£S Universitaires Notre-Dame De La Paix
Curated by ChEMBL
Facult£S Universitaires Notre-Dame De La Paix
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity in presence of MnCl2More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Facult£S Universitaires Notre-Dame De La Paix
Curated by ChEMBL
Facult£S Universitaires Notre-Dame De La Paix
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by plate-based electrochemiluminescent assayMore data for this Ligand-Target Pair