BDBM50184859 CHEMBL204120::N-Cyclohexylcarbonyl-N'-{4-[(6,7-dimethoxy-4-quinolyl)oxy]-phenyl}thiourea

SMILES COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)C4CCCCC4)cc3)c2cc1OC

InChI Key InChIKey=UNMJHOVRTAPNDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184859   

TargetPlatelet-derived growth factor receptor alpha(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184859(N-Cyclohexylcarbonyl-N'-{4-[(6,7-dimethoxy-4-quino...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184859(N-Cyclohexylcarbonyl-N'-{4-[(6,7-dimethoxy-4-quino...)
Affinity DataIC50: 233nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed