BDBM50185172 2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazole::CHEMBL212054

SMILES Fc1ccc2c(-c3nc4ccc(N5CCC(N6CCCCC6)CC5)cc4[nH]3)n[nH]c2c1

InChI Key InChIKey=LRYKPJMJKRDDIX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50185172   

LigandChemical structure of BindingDB Monomer ID 50185172BDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185172BDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human VEGFR2 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185172BDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185172BDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50: 28nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50185172BDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50: 28nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50185172BDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50: 310nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed