BDBM50185182 2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazole::CHEMBL377346

SMILES c1ccc(COc2ccc3[nH]nc(-c4nc5ccc(N6CCC(N7CCCCC7)CC6)cc5[nH]4)c3c2)cc1

InChI Key InChIKey=AQYYPSFZMCKSEL-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50185182   

LigandChemical structure of BindingDB Monomer ID 50185182BDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chiron

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185182BDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50185182BDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chiron

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185182BDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of c-ABLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50185182BDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50185182BDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataEC50:  970nMAssay Description:Antiproliferative activity against K562 cells expressing Bcr-AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed