BDBM50185456 3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethylsulfonyl)-1H-pyrazol-3-yl)butanoic acid::CHEMBL377428

SMILES Cn1nc(CC(CC(O)=O)c2ccc3OCOc3c2)cc1S(=O)(=O)CCc1ccc2CCCNc2n1

InChI Key InChIKey=CTOPQASYIWIPDN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185456   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185456(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50: 1.69nMAssay Description:Inhibition of alpha-v-beta-3 integrin in 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185456(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50: 1.86nMAssay Description:Inhibition of alpha-v-beta-5 integrin in 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185456(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of alpha-v-beta-3 integrin by SPRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185456(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed