BDBM50185466 (S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)-1H-pyrazol-3-yl)butanoic acid::CHEMBL379221

SMILES Cn1nc(C[C@@H](CC(O)=O)c2ccc3OCOc3c2)cc1OCCc1ccc2CCCNc2n1

InChI Key InChIKey=YTAHOLPCQRGOAW-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185466   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185466((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185466((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-...)
Affinity DataIC50:  347nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed