BDBM50185471 3-(benzo[d][1,3]dioxol-5-yl)-4-(1-(2-hydroxyethyl)-5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)-1H-pyrazol-3-yl)butanoic acid::CHEMBL380290

SMILES OCCn1nc(CC(CC(O)=O)c2ccc3OCOc3c2)cc1OCCc1ccc2CCCNc2n1

InChI Key InChIKey=QFUAOXPDMSSGEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185471   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185471(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-(2-hydroxyethyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of alpha-v-beta-3 integrin by SPRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185471(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-(2-hydroxyethyl)...)
Affinity DataIC50: 25.9nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed