BDBM50185472 3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)isoxazol-5-yl)butanoic acid::CHEMBL207563

SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)no1)c1cnc(s1)-c1ccc(Cl)cc1

InChI Key InChIKey=WPRZWONATNXRPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185472   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185472(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(3-(2-(5,6,7,...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of alpha-v-beta-3 integrin by SPRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185472(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(3-(2-(5,6,7,...)
Affinity DataIC50: 131nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed