BDBM50185541 2-(2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-1H-indol-4-yl)-N,N-dimethylethanamine::CHEMBL209537

SMILES CN(C)CCc1cccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1

InChI Key InChIKey=VORUGHSBRGMOOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185541   

TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50185541(2-(2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-...)
Affinity DataIC50: 95nMAssay Description:Displacement of [125I][Tyr14]N/OFQ from ORL1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50185541(2-(2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-...)
Affinity DataIC50: 632nMAssay Description:Antagonist activity against ORL1 receptor by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed