BDBM501856 5-(4-acetylphenyl)-3-(4-aminopiperidin-1-yl)-1-methyl- 6-(4-methylphenyl)pyrazin-2-one::US11028066, Example 94

SMILES CC(=O)c1ccc(cc1)-c1nc(N2CCC(N)CC2)c(=O)n(C)c1-c1ccc(C)cc1

InChI Key InChIKey=RXJPNECUIUQUBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501856   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 501856BDBM501856(5-(4-acetylphenyl)-3-(4-aminopiperidin-1-yl)-1-met...)
Affinity DataIC50: 5.50E+3nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent