BDBM50185789 (R)-1-(3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fluoro-1H-indol-1-yl)-3-(dimethylamino)propan-2-ol::CHEMBL384681

SMILES CN(C)C[C@@H](O)Cn1cc(C2CCN(CC3CCCCCCC3)CC2)c2cc(F)ccc12

InChI Key InChIKey=YEOANUDQDGQSQW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185789   

TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185789((R)-1-(3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fl...)
Affinity DataKi:  970nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185789((R)-1-(3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fl...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185789((R)-1-(3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fl...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185789((R)-1-(3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fl...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed