BDBM50185792 3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole::CHEMBL210770

SMILES Clc1ccc2[nH]cc(C3CCN(Cc4ccccc4)CC3)c2c1

InChI Key InChIKey=NRIVFQIOYWIUPX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185792   

TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185792(3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole | CH...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185792(3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole | CH...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185792(3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole | CH...)
Affinity DataKi:  1.14E+3nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185792(3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole | CH...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed