BDBM50185797 1-((R)-3-amino-2-hydroxypropyl)-3-(1-(1,2-dihydroacenaphthylen-1-yl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-5-carbonitrile::CHEMBL378453

SMILES NC[C@@H](O)Cn1cc(C2=CCN(CC2)C2Cc3cccc4cccc2c34)c2cc(ccc12)C#N

InChI Key InChIKey=CTZWWIABADGLMN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185797   

TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185797(1-((R)-3-amino-2-hydroxypropyl)-3-(1-(1,2-dihydroa...)
Affinity DataKi:  1.65E+3nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185797(1-((R)-3-amino-2-hydroxypropyl)-3-(1-(1,2-dihydroa...)
Affinity DataKi:  4.14E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185797(1-((R)-3-amino-2-hydroxypropyl)-3-(1-(1,2-dihydroa...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185797(1-((R)-3-amino-2-hydroxypropyl)-3-(1-(1,2-dihydroa...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed