BDBM50185807 5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-methyl-1H-indole::CHEMBL212574

SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC2CCCCCCC2)CC1

InChI Key InChIKey=SQLQPFWDGFNBPE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185807   

TargetKappa-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185807(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185807(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Affinity DataKi:  710nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185807(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185807(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Affinity DataKi:  4.18E+3nMAssay Description:Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed