BDBM50185888 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-ethyl-phenylethynyl)-phenylsulfanyl]-butyric acid::CHEMBL379220

SMILES CCc1ccc(cc1)C#Cc1ccc(SC(CCN2C(=O)c3ccccc3C2=O)C(O)=O)cc1

InChI Key InChIKey=PFPAVZNBPUOGBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185888   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185888(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-et...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185888(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-et...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed