BDBM50185981 3,9-di(tert.)butoxycarbonyl-1,7-dihydroxymethyl-6,12-diphenyl-3,9-diazahexacyclo[6.4.0.0(2.7)0(4.11)0(5.10)]dodecane::CHEMBL379211

SMILES CC(C)(C)OC(=O)N1C2C3C4N(C5C(C1[C@@]5(CO)[C@@H]3c1ccccc1)[C@H](c1ccccc1)[C@]24CO)C(=O)OC(C)(C)C

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185981   

TargetATP-dependent translocase ABCB1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50185981(3,9-di(tert.)butoxycarbonyl-1,7-dihydroxymethyl-6,...)
Affinity DataIC50: 3.20E+3nMAssay Description:Cytotoxicity against mouse MDR1 transfected L5178YvMDR cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50185981(3,9-di(tert.)butoxycarbonyl-1,7-dihydroxymethyl-6,...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of P-glycoproteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed