BDBM50186073 CHEMBL210229::N-(2-(dimethylamino)ethyl)-8-isopropyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidine::N-(2-Dimethylamino-ethyl)-8-isopopyl-9-oxo-8,9-dihydro[1,3]thiazolo[5,4-f]quinazoline-2-carboxamidine

SMILES CC(C)n1cnc2ccc3nc(sc3c2c1=O)C(=N)NCCN(C)C

InChI Key InChIKey=QIYPQJHMRBXGMO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50186073   

TargetGlycogen synthase kinase-3 alpha(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186073(N-(2-Dimethylamino-ethyl)-8-isopopyl-9-oxo-8,9-dih...)
Affinity DataIC50: 560nMAssay Description:Inhibition of GSK3alpha/betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186073(N-(2-Dimethylamino-ethyl)-8-isopopyl-9-oxo-8,9-dih...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186073(N-(2-Dimethylamino-ethyl)-8-isopopyl-9-oxo-8,9-dih...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CDK5/p25 in presence of 15 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50186073(N-(2-Dimethylamino-ethyl)-8-isopopyl-9-oxo-8,9-dih...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/cyclinB in presence of 15 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186073(N-(2-Dimethylamino-ethyl)-8-isopopyl-9-oxo-8,9-dih...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186073(N-(2-Dimethylamino-ethyl)-8-isopopyl-9-oxo-8,9-dih...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed