BDBM50186084 CHEMBL210474::N-(2-(dimethylamino)ethyl)-8-ethyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidine::N-(2-Dimethylamino-ethyl)-8-ethyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidine

SMILES CCn1cnc2ccc3nc(sc3c2c1=O)C(=N)NCCN(C)C

InChI Key InChIKey=HGHNNYBSCFYUDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186084   

TargetGlycogen synthase kinase-3 alpha(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186084(N-(2-Dimethylamino-ethyl)-8-ethyl-9-oxo-8,9-dihydr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of GSK3alpha/betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186084(N-(2-Dimethylamino-ethyl)-8-ethyl-9-oxo-8,9-dihydr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50186084(N-(2-Dimethylamino-ethyl)-8-ethyl-9-oxo-8,9-dihydr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CDK1/cyclinB in presence of 15 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed