BDBM50186156 CHEMBL379613::N-{3-[1-(cyclobutylamino)-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxo-2H-1,2,4-benzothiadiazin-7-yl}aminosulfonamide

SMILES NS(=O)(=O)Nc1ccc2N=C(NS(=O)(=O)c2c1)c1c(O)c2ccccc2n(NC2CCC2)c1=O

InChI Key InChIKey=LJLDOPYVVWWDLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186156   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50186156(N-{3-[1-(cyclobutylamino)-4-hydroxy-2-oxo-1,2-dihy...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50186156(N-{3-[1-(cyclobutylamino)-4-hydroxy-2-oxo-1,2-dihy...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed