BDBM50186199 4-Hydroxy-3-(7-hydroxy-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-1-(3-methyl-butyl)-1H-[1,8]naphthyridin-2-one::CHEMBL378174

SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(O)cc3S(=O)(=O)N2)c1=O

InChI Key InChIKey=JYAGCEZVPMLYGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186199   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50186199(4-Hydroxy-3-(7-hydroxy-1,1-dioxo-1,4-dihydro-1lamb...)
Affinity DataIC50: 42nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50186199(4-Hydroxy-3-(7-hydroxy-1,1-dioxo-1,4-dihydro-1lamb...)
Affinity DataIC50: 390nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed