BDBM50186323 3-chloro-N-(6-methylpyridin-2-yl)benzamide::CHEMBL377829

SMILES Cc1cccc(NC(=O)c2cccc(Cl)c2)n1

InChI Key InChIKey=HNLLGNJHYQMYEI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186323   

TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50186323(3-chloro-N-(6-methylpyridin-2-yl)benzamide | CHEMB...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50186323(3-chloro-N-(6-methylpyridin-2-yl)benzamide | CHEMB...)
Affinity DataKi:  1.73E+3nMAssay Description:Displacement of [3H]MPEP from rat brain recombinant mGluR5 expressed in HEK293T cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50186323(3-chloro-N-(6-methylpyridin-2-yl)benzamide | CHEMB...)
Affinity DataIC50: 1.87E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as glutamate-induced calcium flux preincubated for 140 sec before glutamate cha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed