BDBM50186373 CHEMBL424696::N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl)pyridin-2-amine

SMILES C1CCC(CC1)Oc1nccc(n1)-c1cnc(Nc2ccccn2)s1

InChI Key InChIKey=GNHNRVSQWNAGHC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50186373   

TargetCyclin-dependent kinase 9(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186373(N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186373(N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186373(N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl...)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50186373(N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl...)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186373(N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186373(N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl...)
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186373(N-(5-(2-(cyclohexyloxy)pyrimidin-4-yl)thiazol-2-yl...)
Affinity DataIC50: 34nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed