BDBM50186528 CHEMBL212112::cis-1-{3-[(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethoxymethyl]-3-phenyl-cyclobutyl}-pyrrolidin-2-one

SMILES C[C@@H](OC[C@@]1(C[C@@H](C1)N1CCCC1=O)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JHDXXNTYBOADFV-FQQGMQMYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186528   

TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186528(CHEMBL212112 | cis-1-{3-[(R)-1-(3,5-bis-trifluorom...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed