BDBM50186713 (S)-tert-butyl 2-((S)-3-(benzyloxycarbonyl)-4-((S)-1-((S,E)-5-methyl-1-(methylsulfonyl)hex-1-en-3-ylamino)-1-oxopropan-2-ylamino)-4-oxobutanamido)-3,3-dimethylbutanoate::CHEMBL383673

SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N[C@H](C(=O)OC(C)(C)C)C(C)(C)C)NC(=O)OCc1ccccc1)C=CS(C)(=O)=O

InChI Key InChIKey=QVPGEMHCFQRUMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186713   

TargetProteasome subunit beta type-5(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186713((S)-tert-butyl 2-((S)-3-(benzyloxycarbonyl)-4-((S)...)
Affinity DataIC50: 540nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed