BDBM50187002 4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-3-hydroxybenzonitrile::CHEMBL209859

SMILES Oc1cc(ccc1Nc1c(Nc2ccccc2)c(=O)c1=O)C#N

InChI Key InChIKey=GTEDNQAESXZMMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187002   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50187002(4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50187002(4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed