BDBM50187190 7-(4-fluorobenzyl)-9-hydroxy-5-methoxy-6-methyl-6,7-dihydropyrrolo[3,4-g]quinolin-8-one::CHEMBL377267

SMILES COc1c2C(C)N(Cc3ccc(F)cc3)C(=O)c2c(O)c2ncccc12

InChI Key InChIKey=LKXSEJODFICBQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187190   

TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50187190(7-(4-fluorobenzyl)-9-hydroxy-5-methoxy-6-methyl-6,...)
Affinity DataIC50: 88nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in MT4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed