BDBM50187345 (5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)-methanone::CHEMBL207858
SMILES Cc1cccc2[nH]c(cc12)C(=O)c1cc2cc(O)ccc2[nH]1
InChI Key InChIKey=QNNCAUNEIPNZAQ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50187345
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 458nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing wildtype KITMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing KIT V558D mutantMore data for this Ligand-Target Pair