BDBM50187348 (5-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)-methanone::CHEMBL378133

SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2cc(F)ccc2[nH]1

InChI Key InChIKey=LUNUZJNEQKNMPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187348   

TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187348((5-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50:  400nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187348((5-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50:  880nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed