BDBM50187979 4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-((dimethylamino)methyl)pyridin-2-yl)ethynyl)-6-methoxyquinoline-3-carbonitrile::CHEMBL214035

SMILES COc1cc(Nc2c(cnc3cc(C#Cc4cc(CN(C)C)ccn4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=VZCDAZGPTQWPQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187979   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187979(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-((di...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187979(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-((di...)
Affinity DataIC50: 580nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed