BDBM50187984 4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-(2-(6-(2-(4-methylpiperazin-1-yl)ethyl)pyridin-2-yl)ethynyl)quinoline-3-carbonitrile::CHEMBL378484

SMILES COc1cc(Nc2c(cnc3cc(C#Cc4cccc(CCN5CCN(C)CC5)n4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=BQGPIRQVPRBUNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187984   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187984(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187984(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50: 81nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed