BDBM50187986 7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethynyl)-6-methoxy-4-(3,4,5-trimethoxyphenylamino)quinoline-3-carbonitrile::CHEMBL211191

SMILES COc1cc2c(Nc3cc(OC)c(OC)c(OC)c3)c(cnc2cc1C#Cc1cccc(CN(C)C)n1)C#N

InChI Key InChIKey=WTASGERIOJEFKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187986   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187986(7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethyny...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187986(7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethyny...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed