BDBM50187988 7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethynyl)-4-(3,4,5-trimethoxyphenylamino)quinoline-3-carbonitrile::CHEMBL208861

SMILES COc1cc(Nc2c(cnc3cc(ccc23)C#Cc2cccc(CN(C)C)n2)C#N)cc(OC)c1OC

InChI Key InChIKey=CAPPESZVRYKZRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187988   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187988(7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethyny...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187988(7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethyny...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed